Industry Overview – Healthcare
M&A activity in the healthcare sector remains compelling in late 2025, underpinned by strong secular demand, technological transformation, and attractive platforms for private equity consolidation. Despite macroeconomic headwinds such as interest-rate volatility and regulatory scrutiny, both strategics and financial sponsors continue to pursue assets that combine recurring or contractually sticky revenue with scalability.
Key Market Drivers
- Demographic tailwinds + essential demand
An aging population and the growing prevalence of chronic disease support long-term demand for healthcare services. Providers that deliver outpatient, home-based, or preventive care are especially attractive. - Technology integration & digital health Buyers are targeting AI-driven platforms, telehealth, remote monitoring, and workflow automation to reduce costs, improve clinical outcomes, and scale operations.
- Fragmentation in provider services Physician practices, specialty clinics, ambulatory surgery centers (ASCs), home health, and behavioral health remain highly fragmented. This fragmentation offers PE firms opportunities for roll-ups and platform + add-on plays.
- Regulatory & reimbursement pressures While regulation is tightening (especially around PE ownership in care), shifts toward value-based care and outpatient reimbursement (e.g., increased ASC utilization) are supporting scalable provider models.
- Biopharma innovation In biopharma, large-cap players are using the “string-of-pearls” M&A strategy to acquire early- to mid-stage innovation in areas like oncology, immunology, and rare diseases

Valuation and Deal Structure Trends
● Premiums for innovation-driven assets: Health tech and AI-enabled healthcare companies are commanding high valuation multiples as buyers pay up for scalable platforms and data-driven differentiation.
● Provider roll-ups remain central: PE firms continue to build platforms in physician practices, ASCs, and outpatient clinics, particularly in specialties like dentistry, cardiology, and behavioral health.
● Resilience in value-based care models: Practice groups and platforms that have risk-sharing contracts or value-based payment exposure are especially attractive.
● Use of debt + equity mix: While capital conditions are uneven, sponsors are deploying a mix of structured equity, seller earn-outs, and debt. Technology-enabled targets (e.g., health-IT, RCM) often attract growth capital
● Regulatory risk hedging: Given heightened antitrust and PE scrutiny (especially in home health), deals increasingly incorporate longer hold times, lifecycle risk mitigation, and governance structures.
What Drives Up Valuations
- Scalable digital health platforms (telehealth, remote monitoring, AI diagnostics)
- Physician practice platforms (especially in high-growth or fragmented specialties)
- Ambulatory Surgery Centers (ASCs) and hybrid outpatient models
- Home health, hospice, and behavioral health platforms
- Revenue cycle management (RCM) and health IT systems with proven ROI
- Biopharma assets in oncology, rare disease, and immunology (especially mid-stage pipeline)
The Lending Landscape in Healthcare
Lenders generally view healthcare businesses as attractive credit opportunities because they tend to generate steady, recession resistant revenue backed by recurring patient volumes, insurance reimbursements, and ongoing care requirements. Demand is not discretionary, as aging demographics and chronic conditions create a durable need for services, which supports predictable cash flows and borrower stability.
Additionally, lenders appreciate the fragmented nature of the industry, since multi-site roll ups and platform strategies provide scale, lending leverage, and the ability to spread overhead across multiple locations. However, lenders are highly sensitive to regulatory and licensing compliance. This is especially true with SBA 7(a) loans.
Under SBA guidelines, any business that requires a professional or trade license must have a qualified individual holding that license in place before funds are disbursed. If the buyer is not licensed, they must employ someone who is, with clear evidence of managerial authority. If the seller plans to stay on temporarily to support the transition, the SBA typically requires a standby agreement and a written transition plan.
Standalone licenses, billing approvals, and regulatory transfers must be confirmed at or before closing, and SBA lenders routinely verify this during underwriting and in post closing checks. Ultimately, lenders like healthcare because the revenue is defensible and predictable, but SBA and bank lenders will only fund once compliance, licensure, and reimbursement processes are fully documented and tied to the new ownership.

On This Day – Notable Mergers & Acquisitions in November
November 10
- 2023 – Thoma Bravo, a leading software investment firm completes its acquisition of NextGen Healthcare Inc., a leading provider of innovative, cloud-based healthcare technology solutions, for $1.8 billion. https://www.prnewswire.com/news-releases/thoma-bravo-completes-acquisition-of-nextgen-healthcare-301984193.html
November 11
- 2020 – Stryker completes its acquisition of Wright Medical, enhancing their global market position in trauma and extremities. https://investors.stryker.com/press-releases/news-details/2020/Stryker-completes-acquisition-of-Wright-Medical/default.aspx
- 2025 – Cardinal Health acquires Advanced Diabetes Supply Group (ADSG), one of the country’s leading diabetic medical supplies providers, for approximately $1.1 billion in cash. https://newsroom.cardinalhealth.com/2024-11-11-Cardinal-Health-announces-two-strategic-additions-to-its-portfolio
- 2024 – Cardinal Health acquires a majority stake in GI Alliance (GIA), the country’s leading gastroenterology (GI) management services organization. Cardinal Health purchased its majority stake for approximately $2.8 billion in cash, which will represent 71% ownership.https://newsroom.cardinalhealth.com/2024-11-11-Cardinal-Health-announces-two-strategic-additions-to-its-portfolio
November 22
- 2023 – Boehringer Ingelheim acquired bacterial cancer therapy company T3 Pharmaceuticals for $500 Million significantly expanding the German drugmaker’s immuno-oncology pipeline and aligning with some of the company’s existing R&D programs. https://www.fiercebiotech.com/biotech/boehringer-builds-out-cancer-capabilities-acquires-swiss-biotech-deal-worth-508m
November 20
- 2020 – GE Healthcare acquires Prismatic Sensors AB for an undisclosed amount, a leader in Deep Silicon detector technology for photon counting computed tomography, enforcing GE’s position in CT scan technology. https://www.gehealthcare.com/about/newsroom/press-releases/ge-healthcare-pioneers-photon-counting-ct-with-prismatic-sensors-acquisition?srsltid=AfmBOooS-uRuCiiBiYIHioEkr-O0ml3g8R8_V324k_L71QkYiF3rbLBP&utm
November 21
- 2022 – Merck and Co. acquires Imago Biosciences for $1.35 billion to focus on applying our unique capabilities to unlock the value of breakthrough science for the patients they serve. https://www.merck.com/news/merck-to-acquire-imago-biosciences-inc
November 28
- 2018 – CVS health completes its acquisition of Aetna, combining two leading organizations to establish a leading healthcare model in an attempt to make healthcare more affordable and accessible to consumers. https://www.cvshealth.com/news/company-news/cvs-health-completes-acquisition-of-aetna-marking-start-of.html
November 29
- 2022 – AstraZeneca acquires Neogene Therapeutics for $320 million, a global clinical-stage biotechnology company pioneering the discovery, development and manufacturing of next-generation T-cell receptor therapies (TCR-Ts) that offer a novel cell therapy approach for targeting cancer. https://www.astrazeneca.com/media-centre/press-releases/2022/astrazeneca-to-acquire-neogene-therapeutics-accelerating-ambition-in-oncology-cell-therapy.html
November 30
- 2024 – Abbvie acquires Immunogen for roughly $10 billion to continue redefining the standard of care for those living with cancer. https://news.abbvie.com/2024-02-12-AbbVie-Completes-Acquisition-of-ImmunoGen
About Topsail Capital Advisors
Topsail Capital Advisors is a sell-side Mergers & Acquisitions advisory firm focusing on mid-size to lower middle-market, privately held businesses throughout the US. Topsail fills the gap between traditional main street business brokerage firms and the larger investment banking institutions. TCA core services includes valuations, exit planning, sell-side advisory, and capital solutions. Learn more at topsailcapitaladvisors.com.